Monogenic Diabetes
Monogenic Diabetes is caused by a single defect in one of many genes. More than 50 genetic variants have now been reported (at the time of this page update) with the genetic defects affecting different, but specific, aspects of insulin secretion or insulin action. An important feature of these disease-causing mutation is that they appear to be minimally affected by behavioral and environmental factors.
An accurate genetic diagnosis is important in order to ensure appropriate treatment. Here in New Zealand blood samples ca n be sent off to Exeter, UK for diagnostic genetic testing at a cost of approximately $700 per test.
What’s covered on this page:
- Three Decades of Research
- Classification of Monogenic forms of Diabetes
- Maturity Onset Diabetes of the Young (MODY)
- Neonatal Diabetes
- Insulin Resistance Syndromes
Three Decades of Research
Maturity Onset Diabetes of the Young (MODY) was first recognised back in 1974.